About dbCRID

  • dbCRID (Database of Chromosomal Rearrangements In Diseases) is the largest database of curated database of human Chromosome rearrangements and associated diseases.
  • Current release: v 0.9 (06/30/2010).
  • Please direct questions and comments to dbCRID@biolead.org.

    • Related Databases

  • AtlasGeneticsOncology, Atlas of Genetics and Cytogenetics in Oncology and Haematology
  • ChimerDB 2.0, A knowledgebase for fusion genes updated
  • CytoD 1.0, A database of cytogenetic abnormalities.
  • DACRO, A disease-Associated Chromosomal Rearrangements Online.
  • Decipher, , A Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources
  • HYBRIDdb,A database of hybrid genes in the human genome.
  • Mitelman, A database of Chromosome Aberrations and Gene Fusions in Cancer.
  • SKY/M-FISH &CGH, A public platform for investigators to share and compare their molecular cytogenetic data.
  • TICdb, A database of Translocation breakpoints In Cancer.

    • References

  • Kong F, Zhu J, Wu J, Peng J, Wang Y, Wang Q, Fu S, Yuan L and Li T: dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. [PubMed] [Full-text]
    • Event ID: 11777 ( Case ID: 12871 )
    Disease: Tumor All events related to this disease.
    Event Information
    Precision: A
    Chromosome Rearrangement Type: Reciprocal Translocation
    Chromosome: 3, 8
    Karyotype: t(3;8)(p14.2;q24)
    Breakpoints Information:
    First Breakpoint:
    Location: p14.2
    Exact position: Chr3: 60807686bp
    This breakpoint occurs in intron2 of NM_002012.2.
    Second Breakpoint:
    Location: q24
    Exact position: Chr8: 125487531bp
    This breakpoint occurs in extron1 of NM_007218.3.
    Junction Sequence(5'):
    AAAAAATCAAAATTAAGTAAACCTACCTTTCAGAAGACTGCTACCTCTTCGGAGTCCTCAGTGGCAGGATGCACAGAGCTTTTATAGAGGGTCTAAGCAGGGTAAGGGAACAGGGTACCGTACGTCCCGGGACGGCTATGCGGGCCGAGACGTTCCCCGGGGAGCGGGCAGGCGCGCAGAGGCCATGGGTCGAGTATGTG
    Junction Sequence(3'):
    GTGCCCTGCCTTTACATCATCGACGCCATCTTCAACTCCTACCCGGATTCCAGCCAAAGCCGGTTCTGCATCGTGCTCCAGATCTTCCTCCGGCTCTTTGGGCAGGTATTCCTAGGATACCTACACCAAGGACAAGAAATTCAGATGATTATTTCAGCAGTGATCCAGATGGCTCTAGGTACAATTTCATTAGGAACGTT
    The Junction Sequence is Inferred.
    Note: Green and Blue color indicate 5' and 3' sequence according to the breakpoint.
    Experimental Method: Northern blot, DNA sequencing, PCR
    Reference Information
    PubMed ID: 9689122
    Authors: Gemmill RM,West JD,Boldog F,Tanaka N,Robinson LJ,Smith DI,Li F,Drabkin HA
    Journal: Proceedings of the National Academy of Sciences of the United S
    Go to Genome Browser ( Click the image )