About dbCRID

  • dbCRID (Database of Chromosomal Rearrangements In Diseases) is the largest database of curated database of human Chromosome rearrangements and associated diseases.
  • Current release: v 0.9 (06/30/2010).
  • Please direct questions and comments to dbCRID@biolead.org.
  • Related Databases

  • AtlasGeneticsOncology, Atlas of Genetics and Cytogenetics in Oncology and Haematology
  • ChimerDB 2.0, A knowledgebase for fusion genes updated
  • CytoD 1.0, A database of cytogenetic abnormalities.
  • DACRO, A disease-Associated Chromosomal Rearrangements Online.
  • Decipher, , A Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources
  • HYBRIDdb,A database of hybrid genes in the human genome.
  • Mitelman, A database of Chromosome Aberrations and Gene Fusions in Cancer.
  • SKY/M-FISH &CGH, A public platform for investigators to share and compare their molecular cytogenetic data.
  • TICdb, A database of Translocation breakpoints In Cancer.
  • References

  • Kong F, Zhu J, Wu J, Peng J, Wang Y, Wang Q, Fu S, Yuan L and Li T: dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. [PubMed] [Full-text]
  • Event ID: 10752 ( Case ID: 11155 )
    Disease: Acute Myelocytic Leukemia-M3 ( DOID: 12603 ) All events related to this disease.
    Event Information
    Precision: A
    Chromosome Rearrangement Type: Reciprocal Translocation
    Chromosome: 15, 17
    Karyotype: t(15;17)(q22;q21)
    Breakpoints Information:
    First Breakpoint:
    Location: q24.1
    Exact position: Chr15: 74316694bp
    This breakpoint occurs in intron3 of NM_033238.2.
    Second Breakpoint:
    Location: q21.2
    Exact position: Chr17: 38487995bp
    This breakpoint occurs in intron2 of NM_000964.2.
    Junction Sequence(5'):
    Junction Sequence(3'):
    The Junction Sequence is Inferred.
    Note: Green and Blue color indicate 5' and 3' sequence according to the breakpoint.
    Experimental Method: LT-PCR, Bubble PCR, FISH, RT-PCR, DNA sequencing
    Reference Information
    PubMed ID: 12508246
    Authors: Reiter A,Saussele S,Grimwade D,Wiemels JL,Segal MR,Lafage-Pochitaloff M,Walz C,Weisser A,Hochhaus A,Willer A,Reichert A,B├╝chner T,Lengfelder E,Hehlmann R,Cross NC
    Journal: Genes, chromosomes & cancer
    Go to Genome Browser ( Click the image )